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You are here:Home » Antibodies » Abs to Enzymes, Synthetase » Anti -GMP Synthase (GMPS, Glutamine Amidotransferase, Guanine Monphosphate Synthetase, GMP Synthetase) (Azide Free)

Anti -GMP Synthase (GMPS, Glutamine Amidotransferase, Guanine Monphosphate Synthetase, GMP
Synthetase) (Azide Free)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
Catalog #G8245-50
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Immunohistochemistry (paraffin): 1.5ug/ml
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10C403
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant protein corresponding to aa108-216 of human GMPS.
SpecificityRecognizes human GMPS.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesGuanosine 5' Monophosphate Synthase, GMP Synthase [Glutamine-hydrolyzing], EC=6.3.5.2


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