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You are here:Home » Antibodies » Abs to Enzymes, Synthetase » Anti -GMPS (GMP Synthase [Glutamine-hydrolyzing], Glutamine Amidotransferase, GMP Synthetase)

Anti -GMPS (GMP Synthase [Glutamine-hydrolyzing], Glutamine Amidotransferase, GMP
Synthetase)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
Catalog #G8245-50C
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No1D10
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to aa108-216 from human GMPS with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human GMPS.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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