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You are here:Home » Antibodies » Abs to G Proteins » Anti -GNAS (Guanine Nucleotide-binding Protein G(s) Subunit alpha Isoforms Short, Adenylate Cyclase-stimulating G alpha Protein, GNAS1, GSP)

Anti -GNAS (Guanine Nucleotide-binding Protein G(s) Subunit alpha Isoforms Short,
Adenylate Cyclase-stimulating G alpha Protein, GNAS1, GSP)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Catalog #G8250-22A
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 1-3ug/ml, observed in lysates of cell line Jurkat on ~45kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QAARSNSDGEKATK, from human GNAS, at the internal region of the protein (NP_000507.1, NP_001070956.1, NP_001070957.1).
SpecificityRecognizes human GNAS. Species sequence homology: Bovine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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