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You are here:Home » Antibodies » Abs to G Proteins » Anti -GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)

Anti -GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein
Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein
Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Ga16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-b and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling. Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.
Catalog #G8250-31
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Immunohistochemistry: 5-20ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa356 from human G 15.
SpecificityRecognizes human Ga15. Species Crossreactivity: mouse, rat and rabbit.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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