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Abs to G Proteins
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Anti -GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)
Anti -GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein
Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein
Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| Ga16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-b and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling. Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells. | | | Catalog # | G8250-31 | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-4ug/ml | | Immunohistochemistry: 5-20ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa356 from human G 15. | | Specificity | Recognizes human Ga15. Species Crossreactivity: mouse, rat and rabbit. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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