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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -GGA3 (ADP-ribosylation Factor Binding Protein GGA3, Golgi-localized, gamma Ear-containing, ARF-binding Protein 3, KIAA0154)

Anti -GGA3 (ADP-ribosylation Factor Binding Protein GGA3, Golgi-localized, gamma
Ear-containing, ARF-binding Protein 3, KIAA0154)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
GGA3 is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. GGA3 mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins.
Catalog #G8576-88G
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-EQLSTEVGEVDQ, from GGA3, at C-terminal (NP_619525.1, NP_054720.1).
SpecificityRecognizes GGA3. Species sequence homology: Canine, human, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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