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You are here:Home » Antibodies » Abs to G Proteins » Anti -G-Protein, i alpha 2, (Gia2)

Anti -G-Protein, i alpha 2, (Gia2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B
GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation.
Catalog #G8599-08
ApplicationsSuitable for use in Western Blot. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:5001:1000, with detection by 125I-labeled anti-IgG.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No2Q256
HostMouse
SourceBovine
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
PurityPurified
ImmunogenRecombinant Gia-2
SpecificityRecognizes bovine Gia-2 at ~36-49kD. Specificity confirmed by Western Blot versus bovine Gat, rat Goa, rat Gia-1, Gia-2, rat Gia-3, bovine Gsa and mouse GoaA and GoaB. Species sequence homology: mouse, 69%; rat, 69%; human, 62%, guinea pig, 43%
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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