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You are here:Home » Antibodies » Abs to G Proteins » Anti -G Protein, alpha 16, (Ga16)

Anti -G Protein, alpha 16, (Ga16)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Ga16 is the only heterotrimeric G proteins with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. This G protein is known to couple a large number of G protein-coupled receptors to PLC-B and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling. Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.
Catalog #G8599-40
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
TiterWestern Blot: 1:5000
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenE. coli-expressed human Ga16 (aa237-373)
SpecificityReacts with Ga16. Recognizes human Ga16 and mouse Ga15, but not other G proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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