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You are here:Home » Antibodies » Abs to G Proteins » Anti -G Protein alpha Inhibitor 1, 2 (Adenylate cyclase inhibiting G alpha protein, Gi, Gi1 protein alpha subunit, Gi2 protein alpha subunit, GIP, GNAI 1, GNAI 2, GNAI 2B, GNAI1, GNAI2, GNAI2 protein, GNAI2B, GTP binding regulatory protein Gi alpha 2 chain, Gua

Anti -G Protein alpha Inhibitor 1, 2 (Adenylate cyclase inhibiting G alpha protein, Gi,
Gi1 protein alpha subunit, Gi2 protein alpha subunit, GIP, GNAI 1, GNAI 2, GNAI 2B, GNAI1,
GNAI2, GNAI2 protein, GNAI2B, GTP binding regulatory protein Gi alpha 2 chain, Gua

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The G protein family of signal transducers includes the alpha, beta, gamma subunits and the effector which are most clearly distinguished by their different alpha chains. The family also includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein of unknown function that is abundantly expressed in brain; and transducin 1 and 2, proteins involved in retinal phototransduction. The G proteins possess GTPase activity and are components of a complex membrane signaling system that includes membrane-bound receptors. The system exists to modulate extracellular signals as they are transmitted into the cell.
Catalog #G8599-55B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormPBS, 1 mg/ml BSA, 0.05% sodium azide
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: K(346)NNLKDCGLF(355).Immunizing peptide corresponds to amino acid residues 346-355 from human G protein alpha inhibitor 1/2.This sequence is completely conserved in human, rat, guinea pig, hamster, bovine, hydra, octopus, Xenopus, chicken, canine, spiny dogfish, great pond snail, starfish, and American lobster.
SpecificitySpecies Crossreactivity: Crossreacts with Human, Mouse and Rat. Expected to crossreact with bovine, Chicken, canine, Guinea pig, Hamster, Starfish and Xenopus laevis due to sequence homology. Not yet tested in other species.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAdenylate cyclase inhibiting G alpha protein, Gi, Gi1 protein alpha subunit, Gi2 protein alpha subunit, GIP, GNAI 1, GNAI 2, GNAI 2B, GNAI1, GNAI2, GNAI2 protein, GNAI2B, GTP binding regulatory protein Gi alpha 2 chain, Guanine nucleotide binding protein


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