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You are here:Home » Antibodies » Abs to Disease Markers » Anti -G Protein Coupled Receptor 1, Very Large (Very Large G-protein Coupled Receptor 1, VLGR1, VLGR1b, FEB4, G Protein-coupled Receptor 98, G-protein Coupled Receptor 98, GPR98, Monogenic Audiogenic Seizure Susceptibility Protein 1 Homolog, MASS1, USH2B, Usher

Anti -G Protein Coupled Receptor 1, Very Large (Very Large G-protein Coupled Receptor 1,
VLGR1, VLGR1b, FEB4, G Protein-coupled Receptor 98, G-protein Coupled Receptor 98, GPR98,
Monogenic Audiogenic Seizure Susceptibility Protein 1 Homolog, MASS1, USH2B, Usher

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Very Large G Protein-Coupled Receptor-1 (VLGR1) is an Orphan-A GPCR with an unknown ligand. VLGR1 consists of three expressed isoforms. VLGR1 has a large ectodomain containing multiple CALX-beta repeats that resemble regulatory domains of sodium-calcium exchanger proteins. VLGR1b, which is the only form expressed in mouse, is apparently the largest known cell-surface protein with an ectodomain containing 35 CALX- repeats and a pentraxin homology domain. The MASS1 gene, which is a fragment of the very large G-protein-coupled receptor VLGR1, is mutated in the Frings mouse model of audiogenic epilepsy. VLGR1 has been reported to be widely expressed in normal solid tissues. ESTs have been isolated from human adrenal, brain, colon, eye, kidney, nerve, and testis libraries.
Catalog #G8600-04U
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 10-26ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman kidney, renal tubules
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the N-terminal extracellular domain of human Very Large G Protein-Coupled Receptor-1.
SpecificityRecognizes human Very Large G Protein-Coupled Receptor-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDKFZp761P0710, KIAA0686, KIAA1943


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