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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -G Protein Coupled Receptor 15 (GPR15, Brother of Bonzo, BoB, MGC126828, MGC126830)

Anti -G Protein Coupled Receptor 15 (GPR15, Brother of Bonzo, BoB, MGC126828, MGC126830)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
G protein-coupled receptor GPR15 is an Orphan-A GPCR with an unknown ligand. Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use BOB/GPR15 for productive infection, suggesting that this cofactor may play a role in HIV-1 pathogenesis and transmission. GPR15 expression has been reported in CD4(+) T lymphocytes, alveolar macrophages, and the basal surface of the small intestinal epithelium. ESTs have been isolated from normal brain and kidney cancer libraries.
Catalog #G8600-19H
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 13ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman colon
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the C-terminal domain of human GPR15.
SpecificityRecognizes human GPR15.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesG Protein-coupled Receptor 15, G-protein Coupled Receptor 15

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