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You are here:Home » Antibodies » Abs to Receptors, Estrogen » Anti -G-Protein Coupled Receptor 30 (GPCR30, GPR30, CEPR, Chemoattractant Receptor-like 2, CMKRL2, DRY12, Flow-induced Endothelial G-protein Coupled Receptor 1, FEG-1, GPCR-BR, G-protein Coupled Estrogen Receptor 1, GPER, IL8-related Receptor DRY12, LERGU, LERG

Anti -G-Protein Coupled Receptor 30 (GPCR30, GPR30, CEPR, Chemoattractant Receptor-like 2,
CMKRL2, DRY12, Flow-induced Endothelial G-protein Coupled Receptor 1, FEG-1, GPCR-BR,
G-protein Coupled Estrogen Receptor 1, GPER, IL8-related Receptor DRY12, LERGU, LERG

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
GPR30 (G Protein-coupled Receptor 30), also known as G Protein-coupled estrogen Receptor 1 (GPER), is a member of G protein-coupled receptor family. It contains seven hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops. GPR30 transduces a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. GPR30 is an orphan receptor and localizes to the endoplasmic reticulum, where it specifically binds estrogen and estrogen derivatives. Activating GPR30 via estrogen results in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus.
Catalog #G8600-34F
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsELISA: 0.05-0.2ug/ml
Western Blot: 0.5-1ug/ml
Immunohistochemistry: 5-10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, pH 7.4, 0.02% sodium azide. Reconstitute with 80ul sterile ddH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the amino terminal of human GPR30 protein, conjugated to KLH (Swiss Prot: Q99527).
SpecificityRecognizes endogenous levels of human GPR30 protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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