Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -G Protein Coupled Receptor 49 (GPCR49, GPR49, Leucine-rich Repeat Containing G-protein Coupled Receptor 5, Lgr5)

Anti -G Protein Coupled Receptor 49 (GPCR49, GPR49, Leucine-rich Repeat Containing
G-protein Coupled Receptor 5, Lgr5)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH
G-protein coupled receptor GPR49 (also known as Leucine-rich repeat containing G-protein coupled receptor 5, Lgr5) is closely related to members of the glycoprotein hormone receptor subfamily. It is expressed in skeletal muscle, placenta, spinal cord, and various regions of the brain (1). GPR49 is reported to possibly mark stem cells in multiple adult tissues and is over expressed in cancers. G protein-coupled receptor GPR49 is an Orphan-A GPCR with an unknown ligand. GPR49 has been reported to be expressed in brain, skeletal muscle, placenta and spinal cord. ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries, and from human germ cell, uterus and brain (neuroblastoma) cancer libraries.
Catalog #G8600-53B
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1:500-1:1000
Immunoprecipitation: 1:20
Immunohistochemistry (Paraffin): 1:100-1:250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9j103
HostRabbit
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to human GPR49.
SpecificityRecognizes human GPR49 at ~100kD. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links