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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -G Protein Coupled Receptor 56 (GPCR56, GPR56)

Anti -G Protein Coupled Receptor 56 (GPCR56, GPR56)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
G-protein coupled receptor 56 (GPR56) is a novel, multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and containing a characteristic, extracellular GPS domain. Although newly discovered, studies have suggested roles for the protein in the adhesion between developing neurons, regulating the integrity of pial basement membranes, regulating corticogenesis, and may also be involved in cancer cell metastasis and adhesion. Expression has been observed in a wide variety of peripheral tissues, but the most significant levels have been reported in brain, heart and thyroid gland. Defects in GPR56 expression cause bilateral frontoparietal polymicrogyria (BFPP), a malformation of the brain in humans that is characterized by ataxia, seizures, disfigurement of the cerebral cortex, and mental retardation.
Catalog #G8600-60B
ApplicationsSuitable for use in Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry (Paraffin): 1:200 detects GPR56 in inflammatory skin biopsy tissue.
Optimal dilutions to be determined by the researcher.
Positive ControlInflammatory skin biopsy tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in buffer, 0.05% sodium azide, 50% glycerol.
PurityPurified by affinity chromatography.
ImmunogenLinear peptide corresponding to the N-terminus sequence of mouse GPR56 (NP_061370).
SpecificityRecognizes mouse GPR56.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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