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Anti -G Protein Coupled Receptor 132 (Probable G-protein Coupled Receptor 132, GPR132, G2 Accumulation Protein, G2A, MGC99642)
Anti -G Protein Coupled Receptor 132 (Probable G-protein Coupled Receptor 132, GPR132, G2 Accumulation Protein, G2A, MGC99642)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
|
| G2A belongs to the Lysophospholipid/Lysosphingolipid Receptor family and is an anti-proliferative cell cycle regulator that plays a critical role in controlling peripheral lymphocyte homeostasis. Loss of G2A expression leads to the development of a late-onset autoimmune syndrome (Le et al, 2001). Lysophosphatidylcholine (LPC) is the activating ligand for G2A. G2A is expressed in lymphoid tissues. ESTs have been isolated from normal Human primary B-cell from tonsil, leukocyte, colon, lung, and pancreas/spleen, melanocyte/uterus/fetal heart libraries and from a Human bone marrow cancer library. | | | Catalog # | G8602-51A | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 3ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human spleen | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the 2nd cytoplasmic domain of human G2A. | | Specificity | Recognizes human G2A. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | G Protein-coupled Receptor 132 |
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