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Anti -Gr-1 (GR1, Myeloid Differentiation Antigen, Lymphocyte Antigen 6 Complex Locus G, Lymphocyte Antigen 6G, Ly6g, Ly-6G, Ly-6G.1)
Anti -Gr-1 (GR1, Myeloid Differentiation Antigen, Lymphocyte Antigen 6 Complex Locus G,
Lymphocyte Antigen 6G, Ly6g, Ly-6G, Ly-6G.1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
B IP IH FC |
|
| The Gr-1 antigen is a 21-25kD cell surface protein that belongs to the Ly-6 family of proteins. The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes. Expression of Gr-1 on a subpopulation of lymphocytes has also been reported. | | | Catalog # | G8750-01A2 | | Applications | Suitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation and Westen Blot. Reported to deplete mouse mature neutrophils in vivo. Catalog #G8750-01A1 is recommended for functional studies. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:100-1:200; 10ul labels 10e6 cells in 100ul. | | Immunohistochemistry: Frozen sections. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | RB6-8C5 | | Host | Rat | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Normal murine bone marrow cells. | | Specificity | Recognizes mouse Gr-1 antigen. Reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been demonstrated. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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