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You are here:Home » Antibodies » Abs to Proteins » Anti -Gr-1 (GR1, Myeloid Differentiation Antigen, Ly-6G) (FITC)

Anti -Gr-1 (GR1, Myeloid Differentiation Antigen, Ly-6G) (FITC)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Purified B IP IH FC
Ly-6G, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein (1). In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow (2). In the periphery, Ly-6G is expressed predominantly on neutrophils (3, 4).
Catalog #G8750-02A
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot and In vitro activation of complement-dependent cytoxicity Assays. Other applications not tested.
Recommended DilutionFlow Cytometry: 1ug/10e6 cells.
Immunohistochemistry: frozen sections.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone NoRB6-8C5
HostRat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide. Labeled with FITC.
PurityPurified
ImmunogenNormal mouse bone marrow cells.
SpecificityRecognizes mouse Gr-1 at ~21-25kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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