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You are here:Home » Molecular Biology » MB-Binding Proteins » Grancalcin (GCA, EF-Hand Calcium Binding Protein, Penta-EF-Hand Protein) Recombinant, Human

Grancalcin (GCA, EF-Hand Calcium Binding Protein, Penta-EF-Hand Protein) Recombinant,
Human

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Specifications

Grancalcin is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
Catalog #G8925
Species Homo sapiens
Source E. coli
Primary Sequence (aa) 217
Domain (aa) Full-length
Tag/Fusion Partner T7 Tag
Applications Suitable for use in ELISA as an Antigen, Ligand, or Assay Standard. Other applications not tested.
Quality Control SDS-PAGE Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.
Important note This recombinant enzyme has NOT been tested with regard to biological activity.
SourceE. coli
PurityHighly purified
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2. No preservative added.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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