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You are here:Home » Growth Factors, Cytokines » Growth Factors-GM-CSF » Granulocyte Macrophage Colony Stimulating Factor, Recombinant, Human (GM-CSF, Burst Promoting Activity, CMCSF, Colony Stimulating Factor 2, CSF Alpha, Eosinophil Colony Stimulating Factor, Granulocyte Macrophage Colony Stimulating Factor, Molgramostin, Pl

Granulocyte Macrophage Colony Stimulating Factor, Recombinant, Human (GM-CSF, Burst
Promoting Activity, CMCSF, Colony Stimulating Factor 2, CSF Alpha, Eosinophil Colony
Stimulating Factor, Granulocyte Macrophage Colony Stimulating Factor, Molgramostin, Pl

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Specifications

Human GM-CSF is a 14.6kD globular protein consisting of 128 amino acid containing two dislufied bonds. GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells.
Catalog #G8950-33
Recombinant human GM-CSF was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Molecular Weight 14.6kD (128 amino acids)
Sequence
MAPARSPSPS/ TQPWEHVNAI/ QEARRLLNLS/ RDTAAEMNET/ VEVISEMFDL/ QEPTCLQTRL/ ELYKQGLRGS/ LTKLKGPLTM/ MASHYKQHCP/ PTPETSCATQ/ IITFESFKEN/ LKDFLLVIPF/ DCWEPVQE
Endotoxin<1EU/1ug of protein (LAL)
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight14.6 kD
SourceRecombinant, Human, E. coli
Purity95% by SDS PAGE
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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