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You are here:Home » Antibodies » Abs to Signal Transduction » Anti -GRAP2 (GRB2 Related Adaptor Protein 2, GRB2 Like Protein, GADS, GRB2 Related Protein With Insert Domain, GRB2L, GRBLG, GrbX, Grf40, GRID, Growth Factor Receptor Binding Protein, GRPL, SH3-SH2-SH3 Adaptor Molecule)

Anti -GRAP2 (GRB2 Related Adaptor Protein 2, GRB2 Like Protein, GADS, GRB2 Related Protein
With Insert Domain, GRB2L, GRBLG, GrbX, Grf40, GRID, Growth Factor Receptor Binding
Protein, GRPL, SH3-SH2-SH3 Adaptor Molecule)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
Catalog #G8959-13
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:32,000
Western Blot: 1-3ug/ml detects ~38kD band observed lysates of cell line Jurkat (calculated MW of 37.9kD according to NP_004801.1). In transfected HEK293 transiently expressing GRAP2 a band of approx. 40kD is observed. This band is not observed in the non-transfected HEK293.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-GLFPANYVAPMTR, from the C Terminus of human GRAP2 (NP_004801.1).
SpecificityRecognizes human GRAP2. Species sequence homology: mouse, porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMona, Grf40, RP3-370M22.1, growth factor receptor-bound protein 2-related adaptor protein 2, hematopoietic cell-associated adaptor protein GRPL, GRB2-related protein with insert domain, growth factor receptor-binding protein, SH3-SH2-SH3 adaptor molecule,


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