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You are here:Home » Antibodies » Abs to Carbohydrates, Glycoproteins » Anti -GRASP (GRIP associated protein 1, GRIP1 associated protein 1, GRIPAP1, KIAA1167)

Anti -GRASP (GRIP associated protein 1, GRIP1 associated protein 1, GRIPAP1, KIAA1167)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity.
Catalog #G8959-50
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
Form10 mM Hepes (pH7.5), 150 mM NaCl, 100 ug/ml BSA and 50% glycerol
PurityPurified by immunoaffinity chromatography.
ImmunogenPeptide corresponding to amino acid residues from the C-terminal region of rat GRASP, conjugated to keyhole limpet hemocyanin (KLH).
SpecificitySpecific for the ~95k GRASP protein. Species Crossreactivity: Human, mouse, and rat based on 100% antigen sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesGRIP associated protein 1, GRIP1 associated protein 1, GRIPAP1, KIAA1167


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