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Griffonia (Bandeiraea) simplicifolia GS I
Griffonia (Bandeiraea) simplicifolia GS I
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| The seeds of Griffonia simlicifolia conain four distinct lectins. Two of these lectins, referred to as GS-I and GS-II have been well characterized with regard to binding specificity and structure. GS-II is specific for terminal, non-reducing alpha or beta linked N-acetyl-D-glucosamine. This lectin is not blood group specific, unlike GS-I. GS-II is also a tetramer but t is composed of identical subunits. Each subunit has a single carbohydrate binding site for GlcNAc. GS-II is the only lectin isolated that is specific for only a terminal GIcNAc residue. The subterminal saccharide does play an important role in lectin binding. | | | Catalog # | G8967-10 | | Carbohydrate Specificity | Melibiose, alpha-D-Galactose | | Inhibitory Carbohydrate | alpha-Galactose | | Recommended Dilution | 20-30ug/ml is required to agglutinate fresh type B blood cells. Lectin activityy against all blood types increases after neuraminidase treatment of the cells. Optimal dilutions to be determined by the researcher. | | Storage and Stability May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Source | Griffonia (Bandeiraea) simplicifolia | | Concentration | ~1mg/ml. | | Form | Supplied as a liquid in PBS, pH 7.3, and 0.5mM Calcium chloride. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Bandeiraea simplicifolia |
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