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Anti -GRIP1 Associated Protein 1 (GRASP-1, GRASP)
Anti -GRIP1 Associated Protein 1 (GRASP-1, GRASP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity. | | | | | | Applications: | | | Western Blot: 1:1000 | | | Optimal dilutions should be determined by each laboratory for each application. | | | Catalog # | G8970-66 | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Rat | | Form | Supplied as a liquid in 10mM HEPES (pH 7.5), 150mM sodium chloride, 100ug/ml BSA and 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Peptide corresponding to amino acid residues from the C-terminal region of rat GRASP, conjugated to keyhole limpet hemocyanin (KLH) | | Specificity | Specific for the 95kD GRASP in Western Blots of rat cerebellar lysates. Species Crossreactivity: Human and mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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