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You are here:Home » Biochemicals » Biochem-Antibiotics » Griseofulvin (Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533)

Griseofulvin (Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin,
Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533)

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Specifications

Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important asect to the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.
Catalog #G8970-80
Source Penicillium sp.
Apperance White solid
Solubility Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number126-07-8
Molecular FormulaC17H17ClO6
Molecular Weight352.1
SourcePenicillium sp.
Purity~99%
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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