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GRO beta, Recombinant, Human (CXCL2, MIP-2, Macrophage Inflammatory Protein 2)
GRO beta, Recombinant, Human (CXCL2, MIP-2, Macrophage Inflammatory Protein 2)
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| Three human MGSA/GRO genes encode 3 highly related chemokines, MGSA/GRO alpha, -beta and -gamma. All 3 MGSA/GRO proteins bind to the same receptors, but with differing affinities, and stimulate a number of biological responses including chemotaxis, angiogenesis, and growth regulation. | | | Catalog # | G8975-23B | | Biological Activity | GRO-beta is fully biologically active when compared to standard. The Biological activity is calculated by its ability to chemoattract CXCR2 transfected 293 cells using 10.0-100.0ng/ml. | | AA Sequence | APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 8kD | | Source | Recombinant, human, E. coli | | Purity | 98% as determined by RP-HPLC; Reducing and non-reducing SDS-PAGE. | | Form | Supplied as a lyophilized powder from 0.02% TFA. | | Reconstitute with sterile ddH2O to a concentration of 0.1mg/ml. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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