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Growth and Differentiation Factor 9 (GDF9)
Growth and Differentiation Factor 9 (GDF9)
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| Growth differentiation factor 9 (GDF9) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF9 can form non-covalent homodimers when expressed individually, while when GDF9 and BMP15 are co-expressed BMP-15/GDF-9 heterodimers are produced. GDF9 signaling might be transduced by binding to the bone morphogenetic protein receptor (BMPR) type II and one or more BMPR type I receptors. | | | Catalog # | G8989-49D | | Recombinant human GDF-9 is a 31kD non-disulfide-linked homodimer containing two 135 amino acid polypeptide chains. | | Endotoxin | 0.1ng/ug (1EU/ug). | | AA Sequence | GQETVSSELK KPLGPASFNL SEYFRQFLLP QNECELHDFR LSFSQLKWDN WIVAPHRYNP RYCKGDCPRA VGHRYGSPVH TMVQNIIYEK LDSSVPRPSC VPAKYSPLSV LTIEPDGSIA YKEYEDMIAT KCTCR | | Applications | Suitable for use in ELISA, Western Blotting. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage & Stability | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted GDF-9 should be stored in working aliquots at -20°C. | | Country of Origin | USA | | Molecular Weight | 31kD | | Source | E. coli | | Purity | 98% by SDS-PAGE and HPLC analyses. | | Form | Supplied as a lyophilized powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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