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You are here:Home » Biochemicals » Biochem-Molecular Biology » Guanidine Thiocyanate (GuSCN)

Guanidine Thiocyanate (GuSCN)


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Stronger chaotropic agent than Guanidine Hydrochloride. Used in total RNA preparation as ‘guanidinium solution’. Guanidine Thiocyanate is used as a common protein denaturant in the purification and extraction of mRNA, nucleic acids and proteins from cellular material, acting as a strong RNase inhibitor, protecting cellular transcripts from degradation during tissue extraction.
Catalog #G9020
Purity 99%
Appearance White, crystalline powder
Solubility (6M, Water) Colorless, clear, complete
Absorbance280nm: 0.1
300nm: 0.1
410nm: 0.1
pH (4%) 4.5-7.0
Melting Point 115-121ºC
Iron 0.0001%
Heavy Metals 0.0001%
RNase None Detected
DNase None Detected
Protease None Detected
CAS Number593-84-0
Molecular FormulaCH5N3•HSCN
Molecular Weight118.16
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesGuanidine isothiocyanate, Aminomethanamidine thiocyanate

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