Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Enzymes, Cyclase » Anti -Guanylate Cyclase alpha-1, Soluble (GCS-alpha-1, GC-S-alpha-1, GUCY1A1, Guanylate Cyclase 1 Soluble alpha 3, GUC1A3, GUCY1A3, Guanylate Cyclase Soluble Subunit alpha-3, GCS-alpha-3, GC-SA3, GUCA3, GUCSA3, Soluble Guanylate Cyclase Large Subunit)

Anti -Guanylate Cyclase alpha-1, Soluble (GCS-alpha-1, GC-S-alpha-1, GUCY1A1, Guanylate
Cyclase 1 Soluble alpha 3, GUC1A3, GUCY1A3, Guanylate Cyclase Soluble Subunit alpha-3,
GCS-alpha-3, GC-SA3, GUCA3, GUCSA3, Soluble Guanylate Cyclase Large Subunit)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Guanylate cyclase is a heterodimeric protein consisting of an alpha-1 subunit and a beta subunit linked by disulfide bonds. Guanylate cyclase functions as the main receptor for nitric oxide (NO), whereupon it catalyzes the conversion of GTP to the second messenger cGMP. cGMP mediates the vasodilator capacity of NO, and is important in modulating other vascular functions, including cellular proliferation, apoptosis, migration and extracellular matrix production.
Two active isoforms of guanylate cyclase are known to exist; alpha1beta1, and alpha2beta1, of which alpha1beta1 is the principal cardiovascular isoform.
Catalog #G9804-45
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10C447
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant human soluble guanylate cyclase a1ß1 heterodimer.
SpecificityRecognizes human Guanylate Cyclase Alpha-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=4.6.1.2


External Links