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You are here:Home » Antibodies » Abs to Enzymes, Cyclase » Anti -Guanylyl Cyclase beta (GUCY1B3, Guanylate Cyclase Soluble Subunit beta-1, GCS-beta-1, Guanylate Cyclase Soluble Subunit beta-3, GCS-beta-3, Soluble Guanylate Cyclase Small Subunit, GUC1B3, GUCSB3, GUCY1B1)

Anti -Guanylyl Cyclase beta (GUCY1B3, Guanylate Cyclase Soluble Subunit beta-1,
GCS-beta-1, Guanylate Cyclase Soluble Subunit beta-3, GCS-beta-3, Soluble Guanylate
Cyclase Small Subunit, GUC1B3, GUCSB3, GUCY1B1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Soluble guanylyl cyclase catalyses in a Mg2+ or Mn2+ dependent manner, the conversion of guanosine-5'-triphosphate (GTP) to cyclic guanosine- 3',5- monophosphate (cGMP) and pyrophosphate. This enzyme is a major physiological receptor for nitric oxide (NO), an important intra- and intercellular membrane-permanent signaling molecule.
Catalog #G9806-31A
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1:100 for 30min at RT
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10min followed by cooling at RT for 20min.
Optimal dilutions to be determined by the researcher.
Positive ControlBrain
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the aa189-207 of human guanylyl cyclase beta-1soluble.
SpecificityRecognizes human guanylyl cyclase beta. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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