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You are here:Home » Antibodies » Abs to Coenzyme A » Anti -HADH2 (ABAD, ERAB, MHBD, HSD17B10, 17b-HSD10, Hydroxyacyl-Coenzyme A Dehydrogenase Type II, Type 10 17b-HSD, AB-binding Alcohol Dehydrogenase, Type 10 17beta-hydroxysteroid Dehydrogenase)

Anti -HADH2 (ABAD, ERAB, MHBD, HSD17B10, 17b-HSD10, Hydroxyacyl-Coenzyme A Dehydrogenase
Type II, Type 10 17b-HSD, AB-binding Alcohol Dehydrogenase, Type 10 17beta-hydroxysteroid
Dehydrogenase)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Catalog #H1500-02B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.3-2ug/ml. ~ 25kD band observed in Human Brain lysates (calculated MW of 26.9kD according to NP_004484). A minor band of unknown identity was also consistently observed at appr 38kD. This band was successfully blocked by incubation with the immunising peptide.
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide CIRLDGAIRMQP, representing the C-Terminus of the human protein sequence according to NP_004484.
SpecificitySpecies Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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