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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Hamartin (TSC1, Tuberous Sclerosis 1, TSC1, TSC, KIAA0243, LAM, MGC86987)

Anti -Hamartin (TSC1, Tuberous Sclerosis 1, TSC1, TSC, KIAA0243, LAM, MGC86987)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Hamartin, Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors.
Catalog #H1779-01M
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 30% glycerol, 0.5% BSA, 5mM EDTA, 0.01% thimerosal.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1075 of mouse Hamartin.
SpecificityRecognizes mouse Hamartin. Species crossreactivity: human, rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTSC1; TSC; KIAA0243; LAM; MGC86987


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