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Anti -Hamartin (TSC1, Tuberous Sclerosis 1, TSC1, TSC, KIAA0243, LAM, MGC86987)
Anti -Hamartin (TSC1, Tuberous Sclerosis 1, TSC1, TSC, KIAA0243, LAM, MGC86987)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Hamartin, Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. | | | Catalog # | H1779-01M | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1-4ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 30% glycerol, 0.5% BSA, 5mM EDTA, 0.01% thimerosal. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa1075 of mouse Hamartin. | | Specificity | Recognizes mouse Hamartin. Species crossreactivity: human, rat | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | TSC1; TSC; KIAA0243; LAM; MGC86987 |
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