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You are here:Home » Antibodies » Abs to Disease Markers » Anti -HAP1 (Neuroan 1, HLP, HIP5, Huntingtin-Associated Protein 1, RP23-392I3.11, HAP-1, MGC31449)

Anti -HAP1 (Neuroan 1, HLP, HIP5, Huntingtin-Associated Protein 1, RP23-392I3.11, HAP-1,
MGC31449)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified
Huntingtin is the protein product of the gene for Huntington’s disease (HD). HD is a neurodegenerative disorder caused by an expansion of polyglutamine repeats in the huntingtin gene. The HAP1 molecule was reported to bind to the amino terminal region of huntingtin, and enhanced binding correlated with expanded polyglutamine repeats, suggesting a role for HAP1 in the pathogenesis of HD. At least three HAP1 isoforms have been identified but others may exist.
Catalog #H1815-07C
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QDAHSKRQQKQK, from the C Terminus of HAP1(NP_034534.1).
SpecificityRecognizes HAP1. Sequence Homology: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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