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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Hap1 (Huntingtin-associated Protein 1, HAP-1)

Anti -Hap1 (Huntingtin-associated Protein 1, HAP-1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
Huntingtin is the protein product of the gene for Huntington's disease (HD). HD is a neurodegenerative disorder caused by an expansion of polyglutamine repeats in the huntingtin gene. The HAP1 molecule was reported to bind to the amino terminal region of huntingtin, and enhanced binding correlated with expanded polyglutamine repeats, suggesting a role for HAP1 in the pathogenesis of HD. At least three HAP1 isoforms have been identified but others may exist.
Catalog #H1815-07P
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QDAHSKRQQKQK, from the C-terminus of the protein sequence according to NP_034534.1.
SpecificityRecognizes Hap1. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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