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You are here:Home » Antibodies » Abs to Enzymes, Cytochrome » Anti -HCCS (CCHL, Cytochrome c-type Heme Lyase, Holocytochrome c-type Synthase)

Anti -HCCS (CCHL, Cytochrome c-type Heme Lyase, Holocytochrome c-type Synthase)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP
The precursor of cytochrome c, apocytochrome c, is synthesized in the cytoplasm. Upon translocation into mitochondria, cytochrome c acquires a heme moiety required for functionality in the mitochondrial respiration chain. The heme-bound form of cytochrome c is called holocytochrome c. When released into the cytosol, cytochrome c can activate caspases responsible for apoptosis.
Catalog #H1826-80
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 5-10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13A254
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 1% BSA, 0.02% sodium azide, 50% glycerol.
PurityPurified by affinity chromatography.
ImmunogenCytochrome c purified from human heart.
SpecificityRecognizes human Holocytochrome c at ~12kD. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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