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You are here:Home » Antibodies » Abs to Enzymes, Deacetylase » Anti -HDAC1 (Histone Deacetylase 1, HD1, HD-1, HDAC-1, DKFZp686H12203, GON-10, RPD3, RPD3L1, Reduced Potassium Dependency 3 Like-1) (AP)

Anti -HDAC1 (Histone Deacetylase 1, HD1, HD-1, HDAC-1, DKFZp686H12203, GON-10, RPD3,
RPD3L1, Reduced Potassium Dependency 3 Like-1) (AP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH IF
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Catalog #H1827-50T-AP
ApplicationsSuitable for use in ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1.5ug/ml
Western Blot: 1:500-1:1000
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10D51
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Alkaline Phosphatase.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant protein corresponding to aa1-483 of human HDAC1.
SpecificityRecognizes human HDAC1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=3.5.1.98, RPD3 (Reduced Potassium Dependency Yeast Homolog)-like 1


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