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You are here:Home » Antibodies » Abs to Enzymes, Deacetylase » Anti -HDAC1 (HD1, HD-1, HDAC-1, Histone Deacetylase 1, RPD3, RPD3L1, Reduced Potassium Dependency 3, Like-1)

Anti -HDAC1 (HD1, HD-1, HDAC-1, Histone Deacetylase 1, RPD3, RPD3L1, Reduced Potassium
Dependency 3, Like-1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
HDAC1 is an active component of transcriptional corepressor complexes which can be recruited to specific promoter regions via transcriptional factors. HDAC1 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, which leads to the inhibition of gene transcription.
Catalog #H1827-51J
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 0.5-4ug/ml
Immunoprecipitation: 10-20ug/ml
Immunohistochemistry: 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
PurityPurified by Immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the C-terminus of human HDAC1
SpecificityRecognizes human HDAC1 at 62kD. Species crossreactivity: mouse and rat. Does not cross-react with other HDAC proteins including HDAC2, 3, 4, 5, 6, 7 and 8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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