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You are here:Home » Antibodies » Abs to Enzymes, Deacetylase » Anti -HDAC2 (Histone Deacetylase 2, Tanscriptional Regulator Homolog RPD3, HD2)

Anti -HDAC2 (Histone Deacetylase 2, Tanscriptional Regulator Homolog RPD3, HD2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
Catalog #H1827-53K
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormTris-citrate/phosphate buffer, pH 7 to 8
PurityPurified by immunoaffinity chromatography.
ImmunogenThe epitope recognized maps to the N-terminus of human Histone Deacetylase 2 using the numbering given in entry NP_001518.1 (GeneID 3066).
SpecificityThis antibody is specific to the human HDAC2 protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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