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Anti -Heat Shock Protein 104 (HSP104, L0948)
Anti -Heat Shock Protein 104 (HSP104, L0948)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
B IP IC |
|
| Heat Shock Proteins (HSP) are expressed in response to various biological stresses, including high temperatures. There are several major families of HSPs including HSP 70, HSP 90 and HSP 100. The HSP 100 proteins generally have amino acid sequences of about 900 residues and contain two nucleotide-binding sites. Within the HSP 100 family of proteins, yeast express an ~104kD form which is necessary to protect cells from various stress conditions such as heat, heavy metals and ethanol, though mutation studies have shown that the protein is not required for normal growth. Yeast HSP 104 has been shown to be a ClpB protein with significant sequence homology to E. coli ClpB, particularly in the two nucleotide-binding sites. | | | Catalog # | H1833-01A | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Concentration | As reported | | Form | Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide. | | Purity | Whole antisera | | Immunogen | Synthetic peptide: DDDNEDSMEIDDDLD, corresponding to amino acids 894-908 of S. cerevisiae Hsp104. | | Specificity | Species Crossreactivity: Crossreacts with Human, Hamster, Mouse and S. cerevisiae. Does not crossreact with Drosophilia melanogaster, E. coli or Plants. Not yet tested in other species. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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