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You are here:Home » Antibodies » Abs to Heat Shock Proteins » Anti -Heat Shock Protein 105 (Heat Shock 105kDa Protein, Heat Shock Protein 105kD, HSP105, Heat Shock 105kD alpha, HSP105A, Heat Shock 105kD beta, HSP105B, Heat Shock 105kDa Protein 1, Heat Shock 105kDa/110kDa Protein 1, Antigen NY-CO-25, DKFZp686M05240, HSPH1,

Anti -Heat Shock Protein 105 (Heat Shock 105kDa Protein, Heat Shock Protein 105kD, HSP105,
Heat Shock 105kD alpha, HSP105A, Heat Shock 105kD beta, HSP105B, Heat Shock 105kDa Protein
1, Heat Shock 105kDa/110kDa Protein 1, Antigen NY-CO-25, DKFZp686M05240, HSPH1,

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IH
Heat shock protein 105 (Hsp105) exists as two isoforms; alpha and beta which belong to the Hsp105/Hsp110 protein family. Hsp105 acts as both a chaperone to prevent thermal aggregation of proteins and as a regulator of mammalian cells. The Hsp105 isoforms are reported to be found in the cytoplasm but not in the nucleoli under non-stressed and stressed condit-ions. In rodents, Hsp105 isoforms are reported to be moderately expressed in the adrenal glands, spleen, liver and heart and both are markedly increased after heat shock. In the testis, Hsp105 is specifically localized in the cytoplasm of germ cells but may translocate to the nucleus after heat shock. The most abundant expression of Hsp105 occurs in the brain with nuclear and cytoplasmic expression in nearly all neurons, oligodendrocytes, microglia and astrocytes. Increased expression reported during embryogenesis suggests that Hsp105 may have an important role during mouse development.
Catalog #H1833-02B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: Paraffin
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9H362
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid.
PuritySupernatant
ImmunogenProkaryotic recombinant protein of 31kD corresponding to the C-terminus of the heat shock protein 105 molecule.
SpecificityRecognizes human Heat Shock Protein 105. Species Crossreactivity: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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