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Hedgehog (Hh) Signaling Pathway Antagonist (N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea)
Hedgehog (Hh) Signaling Pathway Antagonist (N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinaz olinyl]methyl-urea)
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| Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC50 = 70nM). | | | Catalog # | H1835-60 | | Storage and Stability | Lyophilized powder may be stored at 4°C. Stable for 12 months at 4°C. Reconstitute with sterile DMSO. Aliquot to avoid repeated freezing and thawing. Store at 4°C. Reconstituted product is stable for 6 months at 4°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 330796-24-2 | | Molecular Formula | C23H15ClF4N4O2 | | Purity | ~97% (HPLC) | | Form | Supplied as a white to off-white powder. Reconstitute with DMSO. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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