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You are here:Home » Biochemicals » Biochem-Molecular Biology » Hedgehog (Hh) Signaling Pathway Antagonist (N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea)

Hedgehog (Hh) Signaling Pathway Antagonist
(N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinaz
olinyl]methyl-urea)

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Specifications

Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC50 = 70nM).
Catalog #H1835-60
Storage and StabilityLyophilized powder may be stored at 4°C. Stable for 12 months at 4°C. Reconstitute with sterile DMSO. Aliquot to avoid repeated freezing and thawing. Store at 4°C. Reconstituted product is stable for 6 months at 4°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number330796-24-2
Molecular FormulaC23H15ClF4N4O2
Purity~97% (HPLC)
FormSupplied as a white to off-white powder. Reconstitute with DMSO.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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