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Anti -HepA-Related Protein (HARP, SMARCAL1, EC 3.6.1.-, SIOD)
Anti -HepA-Related Protein (HARP, SMARCAL1, EC 3.6.1.-, SIOD)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| This protein is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. | | | Catalog # | H1887-51 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~2mg/ml | | Form | 0.01% Sodium Azide. 0.15M Sodium Chloride, 0.02M Potassium Phosphate. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide: SNADQRPHDSHSFQAKGC, corresponding to amino acids 80-96 of Human SmarcAL1. | | Specificity | This antibody detects a band at 105kD which corresponds to SmarcAL1. It also detects several lower weight bands of unknown identity. Species Crossreactivity: Reacts with Human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | SMARCA like Protein 1, SWI/SNF Related |
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