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You are here:Home » Antibodies » Abs to Enzymes, Heparanase » Anti -HPSE2 (Heparanase-2, Hpa2, HPA2)

Anti -HPSE2 (Heparanase-2, Hpa2, HPA2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.
Catalog #H1890-96
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1:500-1:3000
Immunohistochemistry (FFPE): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.0, 0.01% thimerosal, 10% glycerol.
PurityPurified by immunoaffinity chromatography
ImmunogenRecombinant protein corresponding to aa260-552 from human HPSE2. Species Sequence Homology: mouse; 100%, rat; 99%
SpecificityRecognizes human HPSE2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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