Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -Heparin Cofactor II (Heparin Cofactor 2, HC2, HCF2, HCII, HC-II, D22S673, HLS2, LS2, Protease Inhibitor Leuserpin-2, Serpin D1, SERPIND1)

Anti -Heparin Cofactor II (Heparin Cofactor 2, HC2, HCF2, HCII, HC-II, D22S673, HLS2, LS2,
Protease Inhibitor Leuserpin-2, Serpin D1, SERPIND1)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Heparin Cofactor II (HCII) is a plasma glycoprotein that is a member of the SERPIN family of proteinase inhibitors. HCII is a relatively specific inhibitor of thrombin and its activity is increased approximately 1000 fold in the presence of heparin. Its activity is also increased in the presence of dermatan sulfate. HCII is a single chain molecule with a mass of 65.6kD. Inhibition of thrombin results in a covalent complex of 102.6kD.
Catalog #H1892-51C
ApplicationsSuitable for use in ELISA, Immunoelectrophoresis and single and double radial immunodiffusion. Other applications not tested.
Recommended DilutionImmunoelectrophoresis: 2ml plasma or equivalent against 120ml antiserum
Double Radial Immunodiffusion: Use a rosette arrangement with 10ml antiserum in 3mm
diameter center well and 2ml plasma samples (neat and serially diluted) in 2mm diameter
peripheral wells.
Single Radial Immunodiffusion: 1% in the gel.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS, pH 7.2. Preservative free. Reconstitute with 1ml sterile dH2O.
PuritySerum
SpecificityRecognizes human Heparin Cofactor II.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSerpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1


External Links