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You are here:Home » Antibodies » Abs to Infectious Disease Hepatitis » Anti -Hepatitis B Surface Antigen, ad,ay (HBsAg)

Anti -Hepatitis B Surface Antigen, ad,ay (HBsAg)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Hepatitis B is an infection of the liver caused by the hepatitis B virus. Approximately 5-10% of adults and 90% of babies who are infected with HBV will go on to carry the virus for the rest of their lives. These people will pass the virus onto others. HBV is excreted in body fluids such as semen, saliva, blood and urine in persons with acute or chronic infection. The route of transmission can include homosexual or heterosexual activity, blood-borne exposure (needles, transfusion), mother-infant, close personal contact and even by consuming contaminated food or water. Thus, Hepatitis B has become a major public health concern. When HBV invades the body it causes liver damage through induction of auto-immunity. Liver cell injury results from cytotoxic T cell activity rather than viral cytotoxic activity. The principal screening test for detecting current (acute or chronic) HBV infection is the identification of HBsAg, an envelope lipoprotein. This is the first immunological marker to appear in a patientís serum and exist in high quantities in the blood. Patients who are HBsAg positive develop chronic persistent hepatitis (CPH) and chronic active hepatitis (CAH). Patients with CPH usually remain in good health. Those with CAH have progressive liver damage with the outcome being portal fibrosis, cirrhosis, or hepatocellular carcinoma.
Catalog #H1909-09D9
Applications
Suitable for use in ELISA and Rapid Assay formats. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Matched PairCapture: H1909-09D8
Detection: H1909-09D9
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8J52
HostMouse
ConcentrationNot Determined
FormSupplied as a lyophilized powder from PBS. Reconstitute with sterile ddH20.
PurityPurified by Protein A chromatography
ImmunogenNative HBsAg (ad/ay).
SpecificityRecognizes all HBsAg A antigens.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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