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Anti -Hepatitis C Virus Core antigen (HCV) (FITC)
Anti -Hepatitis C Virus Core antigen (HCV) (FITC)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IF |
|
| Hepatitis C virus (HCV) represents the major etiologic agent of non-A, non-B hepatitis. The pathological changes in hepatitis C are characterized by the histologic triad of lymphoid aggregates in portal tracts, epithelial damage of small bile ducts and micro-and macro-vesicular steatosis. HCV antigens are visible in the cytoplasm of infected hepatocytes by immunohistochemical staining with mono-or polyclonal antibodies. These studies are important to determine the viral load and expression pattern of HCV in the infected liver. The mechanism of hepatocyte and bile duct injury in HCV infection appears to be related to the host immune response to the virus. Direct viral cytopathogenicity may also play a role. | | | Catalog # | H1920-14 | | Applications | Suitable for use in ELISA and Immunofluorescence. Not suitable for use in Western Blot. Other applications have not been tested. | | Recommended Dilutions | ELISA: Use native viral lysates | | Optimal dilutions to be determined by the researcher. | | Source | Cell culture | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 1.B.348 | | Host | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Labeled with fluorescein isothiocyanate (FITC). | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Recombinant Hepatitis C Virus Core Antigen corresponding to aa80-120. | | Specificity | Recognizes Hepatitis C Virus Core Antigen (aa80-120). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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