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You are here:Home » Antibodies » Antibodies-Infectious Disease Hepatitis » Anti -Hepatitis C Virus Core Antigen (HCV)

Anti -Hepatitis C Virus Core Antigen (HCV)


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Clone Host Grade Applications
Polyclonal Goat Highly Purified E B
Hepatitis C virus (HCV) represents the major etiologic agent of non-A, non-B hepatitis. The pathological changes in hepatitis C are characterized by the histologic triad of lymphoid aggregates in portal tracts, epithelial damage of small bile ducts, and micro-and macro-vesicular steatosis. HCV antigens are visible in the cytoplasm of infected hepatocytes by immunohistochemical staining with mono-or polyclonal antibodies. These studies are important to determine the viral load and expression pattern of HCV in the infected liver. The mechanism of hepatocyte and bile duct injury in HCV infection appears to be related to the host immune response to the virus. Direct viral cytopathogenicity may also play a role.(1)
Catalog #H1920-16
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
Concentration~4-5mg/ml (OD280nm, E0.1% = 1.4)
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by sodium sulfate precipitation and Ion Exchange chromatography (>95%)
ImmunogenRecombinant HCV Core Antigen (genotype 1a)
SpecificityRecognizes the Hepatitis C Virus Core antigen aa1-120.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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