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You are here:Home » Molecular Biology » Growth Factors-HGF » Hepatocyte Growth Factor alpha Chain, Recombinant, Human (Hepatocyte Growth Factor, Hepatopoeitin-A, Scatter Factor, SF, HGF, HPTA)

Hepatocyte Growth Factor alpha Chain, Recombinant, Human (Hepatocyte Growth Factor,
Hepatopoeitin-A, Scatter Factor, SF, HGF, HPTA)

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Specifications

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase-signalling cascade. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69kD alpha-chain and 34kD beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule.
Catalog #H2005-03A
SourceRecombinant corresponding to aa32-494 from mature human HGF-A, fused to 6x His-tag at N-terminal, expressed in E. coli.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~95% (SDS-PAGE)
ConcentrationAs reported
FormSupplied as liquid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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