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You are here:Home » Growth Factors, Cytokines » Growth Factors-HGF » Hepatocyte Growth Factor beta Chain, Recombinant, Human, Western Blot Control (Hepatocyte Growth Factor, Hepatopoeitin-A, Scatter Factor, SF, HGF, HPTA)

Hepatocyte Growth Factor beta Chain, Recombinant, Human, Western Blot Control (Hepatocyte
Growth Factor, Hepatopoeitin-A, Scatter Factor, SF, HGF, HPTA)

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Specifications

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase-signalling cascade. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69kD alpha-chain and 34kD beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule.
Catalog #H2005-04A
SourceRecombinant corresponding to aa495-728 from human mature Hepatocyte Growth Factor beta Chain, fused to 6x His-tag at N-terminal, expressed in E. coli.
ApplicationsSuitable for use in Western Blot as a control. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
PurityPurified (SDS-PAGE)
ConcentrationAs reported
FormSupplied as a liquid in 25mM Tris-HCl, pH6.8, 50mM DTT, 1% SDS, 0.1% Bromophenol Blue, 2.5% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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