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Anti -Hepatocyte Specific Antigen (Hep Par-1, Hepatocyte Paraffin 1, CD 24, CD24A, GPI linked surface mucin Heat stable antigen, Nectadrin Signal transducer, Small cell lung carcinoma cluster 4 antigen)
Anti -Hepatocyte Specific Antigen (Hep Par-1, Hepatocyte Paraffin 1, CD 24, CD24A, GPI
linked surface mucin Heat stable antigen, Nectadrin Signal transducer, Small cell lung
carcinoma cluster 4 antigen)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
IH |
|
| Hepatocyte paraffin 1 (Hep Par1) is a monoclonal antibody that has been developed specifically to react with hepatocytes in routine formalin-fixed and paraffin-embedded surgical pathology tissues. It results in a distinct, granular cytoplasmic staining of hepatocytes but fails to react with bile ducts and nonparenchymal liver cells. The antibody decorates a majority of hepatocellular carcinomas, including fibrolamellar variants. It is also an effective and sensitive marker for hepatocellular differentiation. However the antibody fails to react with a wide variety of other adult malignancies, with the exception of focal staining in a few gastrointestinal malignancies, including a subpopulation of gastric carcinomas. This clone is also referred to as OCH1E5.2.10 in the literature. | | | Catalog # | H2007-01A | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (Paraffin): 1:25-1:50. A 60 minute incubation at RT is recommended. Formalin fixed tissues do not require any special treatment. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human liver | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 8L179A | | Host | Mouse | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. | | Purity | Supernatant | | Immunogen | Human liver fixed in formalin. | | Specificity | Recognizes human hepatocytes. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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