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You are here:Home » Antibodies » Abs to Antimicrobial Peptides » Anti -Hepcidin (HEPC, Liver-expressed Antimicrobial Peptide 1, LEAP-1, Putative Liver Tumor Regressor, PLTR, Hepcidin-25, Hepc25, HAMP, LEAP1, UNQ487/PRO1003)

Anti -Hepcidin (HEPC, Liver-expressed Antimicrobial Peptide 1, LEAP-1, Putative Liver
Tumor Regressor, PLTR, Hepcidin-25, Hepc25, HAMP, LEAP1, UNQ487/PRO1003)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Hepcidin, an human antimicrobial peptide, contains a leader sequence, a proteolysis site and a C-terminal 25aa active peptide. This peptide is most active against gram-positive bacteria, but also inhibits the growth of certain yeast and gram-negative bacteria. HAMP also functions as a signaling molecule involved in the maintenance of iron homeostasis. In conjugation with HFE it seems to regulate both intestinal iron absorption and iron storage in macrophages. Mutations in HAMP are found in juvenile hemochromatosis.
Catalog #H2008-59
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No1F9
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to aa25-85 from human HAMP with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human HAMP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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