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You are here:Home » Antibodies » Abs to Chromatin Proteins » Anti -Heterochromatin Protein 1, beta (HP1-beta, HP1 beta, Chromobox Homolog 1, CBX1, CBX, Heterochromatin Protein p25 beta, HP1Hsbeta, HP1Hs-beta, M31, Modifier 1 Protein, MOD1, p25beta)

Anti -Heterochromatin Protein 1, beta (HP1-beta, HP1 beta, Chromobox Homolog 1, CBX1, CBX,
Heterochromatin Protein p25 beta, HP1Hsbeta, HP1Hs-beta, M31, Modifier 1 Protein, MOD1,
p25beta)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
HP1Hsbeta is one of three mammalian HP1 homologues which localize to centromeric heterochromatin and are characterized by an amino-terminal chromodomain, hinge region and a carboxy-terminal chromoshadow domain. HP1Hsbeta is a component of both pericentric and telomeric heterochromatin and can directly associate with EMSY, TIF1 (transcriptional intermediary factor 1), LBR (lamin B receptor) and CHAF1A (chromatin assembly factor 1, subunit A) via the chromoshadow domain, and with tri-methylated histone H3 lysine 9 via the chromodomain.
Catalog #H2034-51K
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:5000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in tris-citrate/phosphate, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to an epitope between amino acids 50-100 of human HP1Hsbeta (NP_006798.1).
SpecificityRecognizes human HP1Hsbeta (heterochromatin protein 1 homolog beta), a highly conserved nonhistone chromatin component and member of the HP1 family which are involved in heterochromatin formation, transcriptional activation and arrest, gene silencing and chromatin remodelling.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesChromobox Homolog 1 (HP1 beta Homolog Drosophila), Chromobox Protein Homolog 1, Heterochromatin Protein 1 Homolog beta, Heterochromatin Protein p25,


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