Anti -Heterochromatin Protein 1, beta (HP1-beta, HP1 beta, Chromobox Homolog 1, CBX1, CBX,
Heterochromatin Protein p25 beta, HP1Hsbeta, HP1Hs-beta, M31, Modifier 1 Protein, MOD1,
p25beta)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
B |
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| HP1Hsbeta is one of three mammalian HP1 homologues which localize to centromeric heterochromatin and are characterized by an amino-terminal chromodomain, hinge region and a carboxy-terminal chromoshadow domain. HP1Hsbeta is a component of both pericentric and telomeric heterochromatin and can directly associate with EMSY, TIF1 (transcriptional intermediary factor 1), LBR (lamin B receptor) and CHAF1A (chromatin assembly factor 1, subunit A) via the chromoshadow domain, and with tri-methylated histone H3 lysine 9 via the chromodomain. | | | Catalog # | H2034-51K | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000-1:5000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in tris-citrate/phosphate, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to an epitope between amino acids 50-100 of human HP1Hsbeta (NP_006798.1). | | Specificity | Recognizes human HP1Hsbeta (heterochromatin protein 1 homolog beta), a highly conserved nonhistone chromatin component and member of the HP1 family which are involved in heterochromatin formation, transcriptional activation and arrest, gene silencing and chromatin remodelling. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Chromobox Homolog 1 (HP1 beta Homolog Drosophila), Chromobox Protein Homolog 1, Heterochromatin Protein 1 Homolog beta, Heterochromatin Protein p25, |
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Download Specifications for Anti -Heterochromatin Protein 1, beta (HP1-beta, HP1 beta, Chromobox Homolog 1, CBX1, CBX, Heterochromatin Protein p25 beta, HP1Hsbeta, HP1Hs-beta, M31, Modifier 1 Protein, MOD1, p25beta) |
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